Chemotherapy–Induced Colitis
نویسندگان
چکیده
Colitis is a very complex disease entity with several etiologic and pathogenesis charactistics. It may have acute or chronic forms that may be with significant morbidity and negative effect on the quality of life of the patient. While the most common and recognizable forms are those of infectious etiologies, however, other forms include ulcerative, Crohn’s, immunologic, vascular, pseudo membranous, lymphocytic and collagenous types, to name some. Many different classes of pharmaceutical agents, including non-steroidal antiinflammatory agents, cyclooxygenase-2 inhibitors, statins, triptans, anti-viral agents, hormone replacement therapies, antidepressants, and antibiotics, are known to induce colitis.1-4 Colitis is also a well documented side effect of chemotherapy. Chemotherapyinduced colitis may manifest in different clinical settings and have serious sequelae that may impact patient care and outcomes.
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تاریخ انتشار 2012